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Aspergillus Antibody Panel

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Test Description
  • Contact: Serology (319) 335-4291
  • Test Request Form: Serology/Immunology
  • SHL OpenELIS Code: 595, 596, 597
Detection of Aspergillus-specific antibodies to determine recent/active infection
Panel Components
Aspergillus flavus, Aspergillus fumigatus, and Aspergillus niger antibodies
Performed Avg. Turnaround Time Method
Coralville, 8 a.m. - 5 p.m., M-F
5 - 7 business days Immunodiffusion
Fee CPT Code(s)
$90.06 86606 x 3
Specimen Requirements
Specimen Type: Minimum 1 mL Serum
Collection Instructions: Allow blood samples to clot at room temperature prior to centrifugation. Aseptically transfer serum to a tightly closing sterile container for storage.

Red Top Tube: centrifuge and transfer serum to a secondary tube
    Serum Separator Tube: collect 4 - 6 mL and centrifuge
      Shipping:
      Specimens should be stored and shipped under the same conditions. Wrap specimen container in absorbent material and place inside a biohazard bag. Transport specimen with cold pack. Ship to the Coralville location.
      Temperature and Stability: Refrigerate (2-8 degrees C); stable for up to 72 hours. Freeze (-20 degrees C); stable for more than 72 hours.
      Rejection Criteria: Specimens will be rejected if received under these conditions:

      Plasma, CSF. Grossly hemolyzed or lipemic samples as well as samples containing particulate matter or exhibiting obvious microbial contamination should not be tested. Specimens not received in the correct temperature ranges stated under "Temperature and Stability" will be rejected.
      Expected Results:
      Negative, 1 band, 2 bands, 3 bands, 4 bands, 5 bands, 6 bands
      Comments
      Immunodiffusion measures IgG and a positive result may suggest past infection. The test is positive in about 90% of sera from patients with aspergilloma and 50-70% of patients with allergic bronchopulmonary aspergillosis. A negative test (none detected) does not exclude aspergillosis.
      Alternate Names
      Fungal serology; A. flavus, A. niger, A. fumigatus, Aspergillus precipitins
      The University of Iowa

      State Hygienic Laboratory

      General inquires
      SHL Client Services
      319-335-4500 or 1-800-421-IOWA (4692)
      ask-shl@uiowa.edu

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