Test Detail
COVID-19 IgG Antibody
Back to Test Directory| Test Description |
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| Detection of IgG antibodies against SARS-CoV-2 | |||||
| Panel Components | |||||
| CoV-2 IgG arbitrary units (AU/mL) and Interpretation. Serology tests may only be ordered by a healthcare provider. When a provider determines that a SARS-CoV-2 antibody test is needed, the patient should meet one of the following criteria listed at https://covidtesting.shl.uiowa.edu . Please visit this website for additional information regarding COVID-19 testing. | |||||
| Performed | Avg. Turnaround Time | Method | |||
| Coralville, 8 a.m. - 5 p.m., M-F |
6 - 8 business days | Chemiluminescent Immunoassay (CLIA) - DiaSorin TrimericS | |||
| Fee | CPT Code(s) | ||||
| No charge. | 87798 | ||||
| Specimen Requirements | |||||
| Specimen Type: | Minimum 1 mL Serum or Plasma | ||||
| Collection Instructions: |
Serology collection materials are available commercially and should be acquired directly whenever possible. Materials Required: Gold or marble top serum separator tubes (SST), Plastic biohazard specimen bag, Blood draw supplies. SHL currently has a limited supply of SSTs available for order. Please help us conserve these scarce resources by only ordering the number of kits immediately needed and reorder as necessary. Please note that SHL kits do not include any blood draw supplies. Label all specimens with name and date of birth. Ensure the information on the specimen matches the test request form. Unlabeled specimens will be rejected and not tested. Blood should be collected aseptically by venipuncture, allowed to clot, and the serum separated from the clot as soon as possible.
Preferred Specimen: Serum; Gold or Marble Top Serum Separator Tube (SST) (clot activator w/gel); 1 mL minimum; Prefer to have the specimen centrifuged, but not required; Do not need to aliquot. |
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| Temperature and Stability: | Refrigerate (2-8 degrees C); stable for up to 21 days. Freeze (-20 degrees C); stable for more than 21 days. | ||||
| Unacceptable Conditions: | Broken or leaking sample containers; Unlabeled sample containers; Incomplete test request form. Grossly hemolyzed or lipemic samples as well as samples containing particulate matter or exhibiting obvious microbial contamination should not be tested. | ||||
| Expected Results: | |||||
| CoV-2 IgG arbitrary units (AU/mL) and Interpretation (Negative/Positive). | |||||
| Shipping: | |||||
| In accordance with biosafety requirements, make certain that the screw cap tightly seals the tube. Leaking samples will be rejected. Ship to the Coralville location. See Specimen Packaging Guidance at https://covidtesting.shl.uiowa.edu . | |||||
| Comments | |||||
| Serology tests may only be ordered by a healthcare provider. While the RT-PCR molecular test is the test to use for diagnosis of COVID-19, detection of antibodies can serve as an indirect marker of infection. For example, if a provider is considering that there may have been a false negative PCR test, serology might be useful for a patient who has tested negative by the molecular assay, is at least 7 days post onset of symptoms and is not immunocompromised. Serology is useful for screening of recovered COVID-19 patients for donors to convalescent plasma therapy. As a surveillance tool, serologic testing is helpful in estimating the prevalence of past viral infection or the cumulative incidence of infection in a population. It can also help improve our understanding of disease transmission patterns and the proportion of people previously infected, among various populations. It is important to note that there are still many unanswered questions about when to use COVID-19 antibody testing including how detection of antibodies correlates to functional immunity and how long that immunity might last. | |||||
| Alternate Names | |||||
| 2019 Novel Coronavirus IgG/SARS-CoV-2 IgG/Anti-SARS-CoV 2 IgG serologic antibody testing | |||||
