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Ehrlichia IgG Antibody Panel (HGA, HME)

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Test Description
  • Contact: Serology (319) 335-4291
  • Test Request Form: Serology/Immunology
  • SHL OpenELIS Code: 627, 635
Detection of IgG antibodies against Human Granulocytic Anaplasmosis (HGA) or Human Monocytic Ehrlichiosis (HME)
Panel Components
Human Granulocytic Anaplasma and Human Monocytic Ehrlichiosis IgG antibodies
Performed Avg. Turnaround Time Method
Coralville, 8 a.m. - 5 p.m., M-F
5 - 7 business days Indirect Immunofluorescent Assay (IFA)
Fee CPT Code(s)
$50.84 86666 x2
Specimen Requirements
Specimen Type: Minimum 1 mL Serum
Collection Instructions: Allow blood samples to clot at room temperature prior to centrifugation. Aseptically transfer serum to a tightly closing sterile container for storage.

Red Top Tube: centrifuge and transfer serum to a secondary tube
    Serum Separator Tube: collect 4 - 6 mL and centrifuge
      Shipping:
      Specimens should be stored and shipped under the same conditions. Wrap specimen container in absorbent material and place inside a biohazard bag. Transport specimen with cold pack. Ship to the Coralville location.
      Temperature and Stability: Refrigerate (2-8 degrees C); stable for up to 5 days. Freeze (-20 degrees C); stable for more than 5 days.
      Rejection Criteria: Specimens will be rejected if received under these conditions:

      Plasma, CSF. Grossly hemolyzed or lipemic samples as well as samples containing particulate matter or exhibiting obvious microbial contamination should not be tested. Specimens not received in the correct temperature ranges stated under "Temperature and Stability" will be rejected.
      Expected Results:
      Titers of Human Granulocytic Anaplasma and Human Monocytic Ehrlichiosis IgG antibodies present
      Comments
      Human ehrlichiosis is a tick-borne disease caused by rickettsial-like agents. Two forms, human monocytic ehrlichiosis (HME) and human granulocytic anaplasmosis (HGA), have been described. HME is often referred to as spotless or rashless Rocky Mountain spotted fever, and has been reported in various regions of the United States. The causative agent of HME has been identified as Ehrlichia chaffeensis. HGA caused by Anaplasma phagocytophilum is essentially indistinguishable from HME.
      Alternate Names
      Ehrlichia chaffeensis; HME (Human Monocytic Ehrlichiosis); Anaplasma phagocytophilum; HGA (Human Granulocytic Anaplasmosis); Tick Borne Diseases
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      State Hygienic Laboratory

      General inquires
      SHL Client Services
      319-335-4500 or 1-800-421-IOWA (4692)
      ask-shl@uiowa.edu

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