Test Detail
Maternal Screen NTD Serum
Back to Test Directory| Test Description |
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| Screen for risk of Open Neural Tube Defect (NTD). | |||||
| Performed | Avg. Turnaround Time | Method | |||
| Coralville, 8 a.m. - 5 p.m., M-F |
3 - 5 business days | Quantitative Chemiluminescent Immunoassay | |||
| Fee | CPT Code(s) | ||||
| $75.00 | 82105 | ||||
| Specimen Requirements | |||||
| Specimen Type: | Minimum 1 mL Serum | ||||
| Patient Preparation: | Second trimester screening test for Open Neural Tube Defect (spina bifida) drawn between 15 weeks 0 days and 20 weeks 6 days gestation. This test is appropriate for those women who have already had testing or screening for Down Syndrome or Trisomy 18, either by Chorionic Villus Sampling (CVS) or the Maternal Screen First Trimester. | ||||
| Collection Instructions: | Program brochures and patient consent forms are available for order. Red Top Tube: centrifuge and transfer serum to a secondary tube. |
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| Shipping: | |||||
| Specimens should be stored and shipped under the same conditions. Wrap specimen container in absorbent material and place inside a biohazard bag. Transport specimen with cold pack. Ship to the Coralville location. | |||||
| Temperature and Stability: | Refrigerated (2-8°C). Specimen must be received within 9 days of collection. | ||||
| Rejection Criteria: |
Specimens will be rejected if received under these conditions: Plasma. Samples not collected within the required gestational age range for the test requested. Specimens not received in the correct temperature ranges stated under "Temperature and Stability" will be rejected. |
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| Expected Results: | |||||
| MoM values for AFP (NTD screen); Screen Cutoff established for test; Interpretation/Recommended Action: Negative / No further action or Positive / Level II Ultrasound and/or consideration for amniocentesis. | |||||
| Comments | |||||
| The following information is required for test interpretation: Patient's date of birth, current weight, ultrasound date AND measurement, and/or LMP information to date the pregnancy, number of fetuses, patient's race, if patient requires insulin, and if there is a known family history of neural tube defects (NTD). Detection rates: 85% neural tube defects. | |||||
| Alternate Names | |||||
| AFP, AFP only screen, NTD screen | |||||
