The University of Iowa

State Hygienic Laboratory

Breadcrumb

  1. Home
  2. Testing Specialties
  3. Diagnostic and Clinical Testing

Test Detail


Syphilis TPPA

Back to Test Directory
Test Description
  • Contact: Serology (319) 335-4291
  • Test Request Form: Serology/Immunology
  • SHL OpenELIS Code: 1033
Treponema pallidum particle agglutination test (TP-PA). Confirmation test for a negative non-treponemal test method using the reverse syphilis testing algorithm.
Performed Avg. Turnaround Time Method
Coralville, 8 a.m. - 5 p.m., M - F
3 - 5 business days Particle Agglutination
Fee CPT Code(s)
$25.64 86780
Specimen Requirements
Specimen Type: Minimum 1 mL Serum
Collection Instructions: Allow blood samples to clot at room temperature prior to centrifugation. Aseptically transfer serum to a tightly closing sterile container for storage.

Red Top Tube: centrifuge and transfer serum to a secondary tube
    Serum Separator Tube: collect 4 - 6 mL and centrifuge
      Shipping:
      Specimens should be stored and shipped under the same conditions. Wrap specimen container in absorbent material and place inside a biohazard bag. Transport specimen with cold pack. Ship to the Coralville location.
      Temperature and Stability: Refrigerate (2-8 degrees C); stable for less than 5 days. Freeze (-20 degrees C); stable for more than 5 days. May be frozen and thawed once.
      Rejection Criteria: Specimens will be rejected if received under these conditions:

      Plasma, CSF. Grossly hemolyzed or lipemic samples as well as samples containing particulate matter or exhibiting obvious microbial contamination should not be tested. Specimens not received in the correct temperature ranges stated under "Temperature and Stability" will be rejected.
      Expected Results:
      Non Reactive, Inconclusive, Reactive
      Comments
      Treponema pallidum particle agglutination test (TP-PA). Confirmation test for a negative non-treponemal test method using the reverse syphilis testing algorithm.
      Alternate Names
      MHA-TP, Syphilis antibody by MHA, Syphilis TPPA, T pallidum TPPA, T pallidum antibody by MHA, TP-PA, Treponema pallidum Ab, Particle agglutination, Treponema pallidum particle agglutination assay
      The University of Iowa

      State Hygienic Laboratory

      General inquires
      SHL Client Services
      319-335-4500 or 1-800-421-IOWA (4692)
      ask-shl@uiowa.edu

      Footer primary

      • HIPAA Notice of Privacy Practice
      • Copyright 2025 The University of Iowa
      • Privacy Notice
      • UI Nondiscrimination Statement
      • Accessibility